If you have high cholesterol, you may have prescribed medicine for cholesterol to reduce it. Some of the options include Statins, Bempedoic (Nexletol), and ACL inhibitors. Before taking a medicine, it is important to know the side effects. Some of the side effects may be mild, while others can be serious. You should consult your healthcare provider if you experience these side effects.
Statins
Statins are drugs that help lower cholesterol and prevent cardiovascular disease. Cardiovascular disease is the leading cause of death in the United States, so it makes sense to take statins as a first line of therapy. They can reduce the risk of heart attack, stroke, and death by 25 percent. Many doctors prescribe statins to their patients.
The best way to decide if statin therapy is right for you is to know your cholesterol levels and any other risk factors you may have. Your doctor will also consider your risk for heart attacks or strokes to determine which medication would be most effective for you. Typically, a person should aim to keep their total cholesterol level below 200 mg/dL, or 5.2 millimoles per liter.
If you have a family history of cardiovascular disease, your doctor will probably recommend statins to lower your cholesterol. However, many people stop taking statins due to side effects. You should also remember that statins are not for everyone. A doctor may recommend lifestyle changes before prescribing them, and you should always consult with your doctor before taking any medication.
Lovastatin
Lovastatin is a medicine that helps reduce castrol ka ilaj in the blood. It is available in the form of immediate-release and extended-release tablets. The immediate-release type taken before meals, while the extended-release type taken before bedtime. The tablets are not to chewed or crushed. The dose for the immediate-release type is 20 mg. Patients should not take more than 20 mg a day, as this considered low-intensity treatment and will only reduce LDL-C levels by about 30%.
In the past, lovastatin has used to prevent heart disease and strokes. It reduces LDL cholesterol levels by increasing HDL levels, which known as the “good” cholesterol. However, lovastatin is only a one-stop solution for cholesterol, and should use in conjunction with a healthy diet and exercise.
Lovastatin belongs to a group of drugs called HMG-CoA reductase inhibitors. These medicines are effective at lowering high cholesterol and can also slow the progression of coronary artery disease. Lovastatin works by blocking the cholesterol-making enzyme, which causes the blood to contain lower levels of cholesterol. However, it usually takes two to six weeks for it to have any significant effect. Before prescribing lovastatin, your doctor will probably order a blood test to check your cholesterol levels.
Bempedoic (Nexletol)
Bempedoic acid is a cholesterol-lowering medicine used in the treatment of refractory hypercholesterolemia. It has some potential interactions with other medications and should discussed with a healthcare provider prior to starting treatment. Bempedoic acid belongs to a class of long-chain fatty acids with 13 to 21 carbon atoms. Bempedoic acid should not take by pregnant women, as it can harm the unborn baby.
The dosage of Nexletol is usually one tablet per day taken with or without food. It recommended to take it at the same time every day. The medicine will start lowering cholesterol levels immediately after taking it. It should take for eight to twelve weeks before it recommended to stopped should use along with statin therapy. It has proven effective in lowering levels of LDL-C cholesterol in patients with high cholesterol.
Bempedoic acid can decrease LDL-C levels when used in conjunction with cholesterol-lowering medications and lifestyle changes. It works by blocking the production of cholesterol by the liver.
ACL inhibitors
ACL inhibitors work to lower LDL cholesterol levels by inhibiting the production of cholesterol in the liver. This, in turn, allows the liver to produce more low-density lipoprotein. The drug can take on its own or in combination with other lipid-lowering agents. It is also important to follow a healthy diet and exercise program while taking this drug.
In mice, the ACL inhibitor ETC-1002 shown to reduce LDL-C levels. The drug is also effective in a DKO mouse model that eliminates AMPK signaling. It also inhibits the activity of the enzyme HMG-CoA, a key enzyme in the biosynthesis pathway of cholesterol in the liver.
ETC-1002 is an example of a competitive ACL inhibitor. It inhibits the enzyme by reducing ACL protein levels. It also increases the activity of the LDL-receptor by 3.2-fold compared to atorvastatin alone also reduces the activity of HMG-CoA reductase, another important enzyme in the liver.
Another class of non-statin therapy is bempedoic acid. It inhibits cholesterol biosynthesis in the liver and has shown promising results in clinical trials. It has tested as a monotherapy, as well as in combination with statins in patients with statin intolerance is FDA-approved for use as an adjunct to maximally tolerated statin therapy. Further studies are being conducted to evaluate the effects of bempedoic acid on cardiovascular risk and outcomes.
Plant stanols
Plant stanols are compounds that can reduce levels of LDL-C in the blood. They work by partially blocking the absorption of cholesterol, but this effect is not permanent. Commercial food products contain plant stanols, and their intake can reduce LDL-C levels by up to 10%. These compounds absorbed in the gastrointestinal tract at very low doses and are generally considered safe. In fact, clinical trials have not reported any side effects or significant changes in clinical indicators.
Plant stanols are available in soft gels, supplements, and dietary oils. They have also incorporated into reduced-fat spreads and margarine. They are safe for most adults, although they should not taken by pregnant or breastfeeding women or children under five.
Several studies show that dietary plant sterols lower cholesterol. However, more studies needed to determine how effective they are in lowering blood cholesterol levels. While the effects of dietary plant sterols on LDL cholesterol levels are still inconclusive, some have shown some positive results. One study found that plant sterols reduced cholesterol levels in adults with mild hypercholesterolaemia and slight obesity.
Other medications
If you are having trouble controlling your cholesterol, you may want to consider other medications. There are many options available, and most work best in conjunction with healthy eating and exercise. If you are thinking about trying a new medication, talk to your doctor about the right one for your needs. This way, you will get the maximum benefit from the medicine.
Fibrates are a type of cholesterol medication that helps the liver break down fats in the blood. Fibrates can take alone or in combination with other medications. The dosage based on the patient’s age, medical history, and response to the medication. Fibriates can have some side effects, but these vary from person to person.
The most common cholesterol medication is a statin. It works by inhibiting an enzyme in the liver that makes cholesterol, reducing the amount of cholesterol produced. It’s safe and effective and may reduce your risk of heart attack and stroke. It’s best to take statins as directed by your doctor if you have a history of heart attacks.
Side effects
When you take medicine for cholesterol kam karny ka Unani ilaaj, you may experience certain side effects. These known as adverse drug reactions, and they can occur from the first few days to several weeks after you start taking the medication. While most of these effects are minor, some of them can be severe enough to cause you to stop taking the medication. If you experience any of these effects, contact your healthcare provider to discuss your options. Your doctor may need to adjust your cholesterol medicine to prevent side effects.
One of the most popular types of medicine for cholesterol is a type of drug called a statin. This medication lowers cholesterol in the blood and helps prevent heart attacks and strokes. Studies show that taking statins can reduce the risk of heart attack and stroke by up to 25% and of recurrent strokes by up to 40%. However, these drugs can also cause other side effects, including muscle pain and digestive problems.